Description

2-[3,5-Bis(Trifluoromethyl)Phenyl]Ethanethioamide is a high-value, fluorinated organic building block characterized by its unique phenyl ethanethioamide core flanked by two trifluoromethyl groups. This compound matters as a critical intermediate in advanced pharmaceutical and agrochemical synthesis, where its structural motifs confer desirable properties like metabolic stability and enhanced lipophilicity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting neurological disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the bioactivity of the trifluoromethylphenyl moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Investigated as a monomer or additive for developing advanced polymers with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CMOs for client-specific custom synthesis projects requiring fluorinated thioamide derivatives.

Basic Information

Product Name	2-[3,5-Bis(Trifluoromethyl)Phenyl]Ethanethioamide
CAS No.	691868-49-2
Molecular Formula	C10H5F6NS
Molecular Weight	285.21 g/mol
Synonyms	2-[3,5-Bis(trifluoromethyl)phenyl]ethanethioamide; 3,5-Bis(trifluoromethyl)phenethylthioamide; Ethanethioamide, 2-[3,5-bis(trifluoromethyl)phenyl]-; 2-(3,5-Bis(trifluoromethyl)phenyl)ethanethioamide; 691868-49-2; α-(3,5-Bis(trifluoromethyl)phenyl)thioacetamide
EINECS	Contact for details

Quality Control

Our 2-[3,5-Bis(Trifluoromethyl)Phenyl]Ethanethioamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing all quality parameters are provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.