Description

4-Pentenoic Acid, 2-[(2-Methyl-1-Oxopropyl)Amino]- is a specialized, high-purity chemical intermediate featuring a reactive pentenoic acid backbone and a protected amino acid derivative. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecules with precise stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in peptide mimetics, active pharmaceutical ingredient (API) development, and novel material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting protease inhibition or requiring specific chiral centers.
• Peptidomimetic Synthesis: Used to construct non-peptide scaffolds that mimic the structure and function of natural peptides, enhancing metabolic stability for therapeutic applications.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: The reactive alkene and amide functionalities allow for site-specific modification of biomolecules in biotech research.
• Academic and R&D Laboratories: Employed in methodological development and the exploration of new synthetic pathways in organic chemistry.
• Specialty Polymer Modification: Can be incorporated into polymer chains to introduce functional handles for further chemical modification or to alter material properties.

Basic Information

Product Name	4-Pentenoic Acid, 2-[(2-Methyl-1-Oxopropyl)Amino]-
CAS No.	690684-46-9
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	2-[(2-Methylpropanoyl)amino]pent-4-enoic acid; 2-(Isobutyrylamino)pent-4-enoic acid; N-Isobutyl-4-pentenoic acid amide derivative; 4-Pentenoic acid, 2-[(2-methyl-1-oxopropyl)amino]-; 2-Amino-4-pentenoic acid, N-isobutyryl derivative; (S)- or (R)-2-(2-Methylpropionamido)pent-4-enoic acid (stereoisomers); UNII-Contact for details
EINECS	Contact for details

Quality Control

Our 4-Pentenoic Acid, 2-[(2-Methyl-1-Oxopropyl)Amino]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specific enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.