Description

Boronic Acid, [4-(Difluoromethoxy)Phenyl]- (9Ci) is a specialized organoboron compound characterized by its unique difluoromethoxy-substituted phenyl ring. This structural motif makes it a valuable synthetic intermediate, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical researchers and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials where the introduction of a boronic acid handle is required.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially in medicinal chemistry programs targeting various disease areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Essential for forming carbon-carbon bonds in the production of complex biaryl structures, a common scaffold in many bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluoromethoxy group can enhance biological activity and stability.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysts, and other functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	Boronic Acid, [4-(Difluoromethoxy)Phenyl]- (9Ci)
CAS No.	688810-12-0
Molecular Formula	C7H7BF2O3
Molecular Weight	187.94 g/mol
Synonyms	[4-(Difluoromethoxy)phenyl]boronic acid; 4-(Difluoromethoxy)benzeneboronic acid; (4-Difluoromethoxyphenyl)boronic acid; B-[4-(Difluoromethoxy)phenyl]boronic acid; 4-Difluoromethoxybenzeneboronic Acid; Boronic acid, B-[4-(difluoromethoxy)phenyl]-; 688810-12-0; (4-(Difluoromethoxy)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, [4-(Difluoromethoxy)Phenyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.