Description

Orlistat Tetradecyl Ester is a synthetic ester derivative of the active pharmaceutical ingredient orlistat, designed for specialized research and development applications. This compound is valued for its role as a key intermediate in the synthesis of novel lipase inhibitors and for studying structure-activity relationships in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on metabolic disorder therapeutics and advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the research and development of new lipase inhibitor drugs and prodrugs.
• Biochemical Research: Used in in-vitro studies to investigate pancreatic and gastric lipase inhibition mechanisms.
• Medicinal Chemistry: Serves as a reference standard or a synthetic precursor for creating analogs to explore pharmacophore models.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical entities.
• Academic Research: Utilized in university and institutional labs for metabolic and enzymatic studies.

Basic Information

Product Name	Orlistat Tetradecyl Ester
CAS No.	686744-60-5
Molecular Formula	C46H81NO5
Molecular Weight	728.2 g/mol
Synonyms	N-Formyl-L-leucine (3S,4S)-3-hexyl-4-{[(2S)-2-(tetradecyloxycarbonyl)pentadecanoyl]oxy}oxetan-2-yl ester; Tetradecyl (2S)-2-({[(1S)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]carbamoyl}-3-methylbutyl]carbamoyl}oxy)pentadecanoate; Orlistat Tetradecyl Ester; Lipase Inhibitor Tetradecyl Ester; Orlistat C14 Ester
EINECS	Contact for details

Quality Control

Our Orlistat Tetradecyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.