Description

(Rs)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Propylamine is a high-value chiral amine building block characterized by its electron-deficient aromatic system and trifluoromethyl groups, which impart unique physicochemical properties. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structural features can enhance metabolic stability and bioavailability. It is primarily sought after by research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Key chiral intermediate in the synthesis of pharmaceutical candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Building block for advanced agrochemicals, including herbicides and fungicides, leveraging the bioactivity of the trifluoromethylphenyl moiety.
• Ligand precursor in asymmetric catalysis and coordination chemistry for developing novel catalytic systems.
• Monomer or functionalizing agent in the production of specialty polymers and advanced materials with specific surface properties.
• Intermediate for analytical standards and reference materials used in quality control and regulatory testing.
• Starting material in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	(Rs)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Propylamine
CAS No.	685503-45-1
Molecular Formula	C12H11F6N
Molecular Weight	283.21 g/mol
Synonyms	1-[3,5-Bis(trifluoromethyl)phenyl]propan-1-amine; (R/S)-1-[3,5-Bis(trifluoromethyl)phenyl]propylamine; α-Methyl-3,5-bis(trifluoromethyl)benzenemethanamine; 3,5-Bis(trifluoromethyl)benzeneethanamine, α-methyl-; (RS)-1-(3,5-Bis(trifluoromethyl)phenyl)propylamine; 1-(3,5-Bis(trifluoromethyl)phenyl)propylamine (racemic); rac-1-[3,5-Bis(trifluoromethyl)phenyl]propylamine
EINECS	Contact for details

Quality Control

Our production of (Rs)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Propylamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot is subjected to comprehensive analytical testing, including chiral purity analysis, to confirm identity and specification compliance. A Certificate of Analysis (COA) detailing specific results for purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.