Description

2-Methoxy-5-(Trifluoromethyl)Benzyl Bromide is a versatile and high-value benzyl bromide derivative, distinguished by its methoxy and trifluoromethyl substituents. This compound is a critical building block in advanced organic synthesis, prized for its reactivity as an alkylating agent and the unique properties imparted by the trifluoromethyl group. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors seeking to introduce functionalized benzyl motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Biology Probes: Useful for modifying biomolecules or creating activity-based probes for studying enzyme function.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Benzyl Bromide
CAS No.	685126-88-9
Molecular Formula	C9H8BrF3O
Molecular Weight	269.06 g/mol
Synonyms	1-(Bromomethyl)-2-methoxy-5-(trifluoromethyl)benzene; α-Bromo-2-methoxy-α,α,α-trifluoro-p-xylene; 2-Methoxy-α,α,α-trifluoro-p-tolyl bromide; (2-Methoxy-5-(trifluoromethyl)phenyl)methyl bromide; 5-(Trifluoromethyl)-2-methoxybenzyl bromide; 2-Methoxy-5-trifluoromethylbenzyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxy-5-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality management systems and undergoes rigorous analytical testing. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.