Description

3-Fluorophenylboronic Acid-1,3-Propanediol Ester is a specialized boronic ester derivative, a protected form of 3-fluorophenylboronic acid, valued for its enhanced stability and handling properties in sensitive synthetic workflows. This compound serves as a crucial building block in modern cross-coupling reactions, enabling the precise construction of complex fluorinated aromatic systems. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel fluorinated drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides that incorporate fluorinated aromatic rings for improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Production: Acts as a precursor for creating fluorinated organic semiconductors and charge-transport materials used in display and lighting technologies.
• Polymer & Resin Modification: Employed to introduce fluorophenyl groups into polymer backbones, enhancing material properties like chemical resistance, thermal stability, and surface characteristics.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science labs for exploring structure-activity relationships and new molecular entities.
• Diagnostic Reagent Synthesis: Utilized in the preparation of fluorinated probes and tags for bioimaging and diagnostic assays.

Basic Information

Product Name	3-Fluorophenylboronic Acid-1,3-Propanediol Ester
CAS No.	684648-38-2
Molecular Formula	C9H10BFO2
Molecular Weight	180.0 g/mol
Synonyms	3-Fluorophenyl-1,3,2-dioxaborinane; 3-Fluorobenzeneboronic Acid 1,3-Propanediol Ester; 2-(3-Fluorophenyl)-1,3,2-dioxaborinane; 3-Fluorophenylboronic Acid Cyclic Propylene Ester; 3-Fluorophenylboronic Acid Neopentyl Glycol Ester Analog; 3-Fluorophenyl-1,3,2-dioxaborolane Homolog; B-(3-Fluorophenyl)-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 3-Fluorophenylboronic Acid-1,3-Propanediol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment. We support development and scale-up with custom purity grades and documentation tailored to cGMP, ISO, or other regulatory requirements as needed.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; containers must be sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.