Description

2-Chloro-3-Fluorobenzamide is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and environmental stability.
• Ligand and Catalyst Development: Used in academic and industrial research to create novel ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals where halogenated benzamide units impart specific electronic or physical properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-3-Fluorobenzamide
CAS No.	683274-49-9
Molecular Formula	C7H5ClFNO
Molecular Weight	173.57 g/mol
Synonyms	2-Chloro-3-fluorobenzoic acid amide; 3-Fluoro-2-chlorobenzamide; Benzamide, 2-chloro-3-fluoro-; 2-Chloro-3-fluorobenzenecarboxamide; o-Chloro-m-fluorobenzamide; 683274-49-9; Amide of 2-chloro-3-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluorobenzamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.