Description

3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Heptanoic Acid is a specialized Fmoc-protected amino acid derivative, a crucial building block in modern solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled, sequential assembly of complex peptides by protecting the amino group during chain elongation. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid building block for the controlled assembly of custom peptide sequences.
• Pharmaceutical R&D: For the research and development of novel peptide-based therapeutics, including hormones, antibiotics, and targeted drug candidates.
• Bioconjugation: Used to introduce specific functional handles or linkers into peptides for conjugation with other molecules, such as dyes, polymers, or drug payloads.
• Combinatorial Chemistry: A vital component in libraries for high-throughput screening to discover new bioactive compounds.
• Peptide Library Production: Enables the synthesis of diverse peptide arrays for epitope mapping, vaccine development, and biomarker discovery.
• Academic & Institutional Research: Supports fundamental studies in biochemistry, molecular biology, and medicinal chemistry.

Basic Information

Product Name	3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Heptanoic Acid
CAS No.	683219-85-4
Molecular Formula	C22H25NO4
Molecular Weight	367.44 g/mol
Synonyms	Fmoc-3-aminoheptanoic acid; Fmoc-Ahx-OH; Fmoc-6-aminohexanoic acid (common misnomer based on carbon count); N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-aminoheptanoic acid; 3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]heptanoic acid; Fmoc-β-homoalanine pentyl ester (open acid form); Nα-Fmoc-3-aminohaptanoic acid; Fmoc-3-Ahx-OH
EINECS	Contact for details

Quality Control

Our 3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Heptanoic Acid is manufactured under strict quality systems to ensure consistency and reliability for sensitive synthetic applications. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.