Description

3-(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}-3-(4-Hydroxyphenyl)-Propanoic Acid is a specialized Fmoc-protected amino acid derivative, serving as a critical building block in solid-phase peptide synthesis (SPPS). Its core value lies in enabling the precise and efficient construction of complex peptides and peptidomimetics, where the Fmoc group provides orthogonal protection for the amine functionality. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly those developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the stepwise assembly of peptides using Fmoc chemistry protocols.
• Pharmaceutical Research: Used in the research and development of novel peptide-based drugs and therapeutic agents.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening and drug discovery.
• Proteomics & Biochemical Studies: Utilized in the synthesis of substrate analogs, enzyme inhibitors, and probes for studying protein function.
• Material Science: Can be incorporated into peptide-based polymers or biomaterials for specialized applications.

Basic Information

Product Name	3-(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}-3-(4-Hydroxyphenyl)-Propanoic Acid
CAS No.	683218-27-1
Molecular Formula	C24H21NO5
Molecular Weight	403.43 g/mol
Synonyms	Fmoc-Tyr(3-OH)-OH; Fmoc-3-hydroxy-L-tyrosine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-hydroxy-L-tyrosine; (2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-hydroxyphenyl)propanoic acid; 3-Hydroxy-L-tyrosine, N-Fmoc derivative; Fmoc-3-hydroxytyrosine; Fmoc-L-Tyr(3-OH)-OH; Fmoc-3-OH-Tyr-OH
EINECS	Contact for details

Quality Control

Our 3-(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}-3-(4-Hydroxyphenyl)-Propanoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research and synthesis applications. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.