Description

3-Cyclohexyl-3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Propionic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern peptide synthesis. Its primary value lies in enabling the precise and efficient construction of complex peptide chains, particularly those requiring the incorporation of the non-proteinogenic amino acid 3-cyclohexylalanine. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, where it is used to develop novel therapeutic peptides, peptide hormones, and diagnostic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated, stepwise assembly of custom peptide sequences.
• Pharmaceutical Research & Development: For the synthesis of peptide-based drug candidates, including metabolic regulators, antimicrobial peptides, and targeted therapeutics.
• Bioconjugation: Serving as a linker or spacer molecule for attaching peptides to other biomolecules, polymers, or surfaces in drug delivery system development.
• Combinatorial Chemistry Libraries: Used to create diverse libraries of peptide analogs for high-throughput screening against biological targets.
• Academic & Institutional Research: A fundamental reagent in biochemistry and medicinal chemistry laboratories for studying protein structure-function relationships and designing peptide mimetics.

Basic Information

Product Name	3-Cyclohexyl-3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Propionic Acid
CAS No.	683217-52-9
Molecular Formula	C24H27NO4
Molecular Weight	393.48 g/mol
Synonyms	Fmoc-3-cyclohexyl-Ala-OH; Fmoc-3-cyclohexylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-cyclohexyl-L-alanine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclohexylpropanoic acid; Fmoc-Cha-OH; Fmoc-L-3-cyclohexylalanine; Nα-Fmoc-3-cyclohexyl-L-alanine; N-Fmoc-3-cyclohexylalanine
EINECS	Contact for details

Quality Control

Our 3-Cyclohexyl-3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-Propionic Acid is manufactured under strict quality systems to meet the exacting standards of peptide synthesis. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); therefore, containers should be kept sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.