Description

2,6-Bis(Trifluoromethyl)Benzeneboronic Acid is a high-value organoboron building block characterized by its electron-deficient aromatic core and trifluoromethyl substituents. This compound is essential for facilitating challenging cross-coupling reactions, particularly in the synthesis of complex, fluorinated molecules. It is a critical reagent for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where its unique structure enables the introduction of sterically hindered, fluorinated aromatic systems.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-couplings for synthesizing active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl groups enhance lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and polymerization processes.
• Advanced Materials Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for electronic and photonic applications.
• Chemical Biology & Diagnostics: Utilized in probe and tracer molecule synthesis for imaging and diagnostic assays.

Basic Information

Product Name	2,6-Bis(Trifluoromethyl)Benzeneboronic Acid
CAS No.	681812-07-7
Molecular Formula	C9H5BF6O2
Molecular Weight	269.94 g/mol
Synonyms	2,6-Bis(trifluoromethyl)phenylboronic Acid; [2,6-Bis(trifluoromethyl)phenyl]boronic Acid; Benzeneboronic Acid, 2,6-bis(trifluoromethyl)-; 2,6-Di(trifluoromethyl)benzeneboronic Acid; B-[2,6-Bis(trifluoromethyl)phenyl]boronic Acid
EINECS	Contact for details

Quality Control

Every batch of 2,6-Bis(Trifluoromethyl)Benzeneboronic Acid is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.