Description

Bicyclo[5.1.0]Octane-8-Carboxamide, (1Alpha,7Alpha,8Alpha)- (9Ci) is a high-purity, specialized bicyclic organic compound with a defined stereochemistry, serving as a critical building block in advanced synthetic chemistry. Its unique strained ring structure and functionalized carboxamide group make it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in programs targeting central nervous system (CNS) disorders or anti-infectives.
• Agrochemical Synthesis: Used in the development of novel pesticides or herbicides, where its bicyclic framework can contribute to unique biological activity and selectivity.
• Advanced Material Research: Serves as a precursor or monomer in the synthesis of specialized polymers or functional materials with specific mechanical or optical properties.
• Catalyst Ligand Development: The defined stereocenters and rigid structure make it a candidate for developing novel chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in academic and industrial research to create molecular probes for studying enzyme function or cellular pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Bicyclo[5.1.0]Octane-8-Carboxamide, (1Alpha,7Alpha,8Alpha)- (9Ci)
CAS No.	681453-20-3
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	(1α,7α,8α)-Bicyclo[5.1.0]octane-8-carboxamide; Bicyclo[5.1.0]octane-8-carboxamide, (1α,7α,8α)-; 8-Bicyclo[5.1.0]octanecarboxamide, (1α,7α,8α)-; (1Alpha,7Alpha,8Alpha)-Bicyclo[5.1.0]octane-8-carboxamide; (1α,7α,8α)-Octahydro-1,7-methanoindene-8-carboxamide
EINECS	Contact for details

Quality Control

Our Bicyclo[5.1.0]Octane-8-Carboxamide, (1Alpha,7Alpha,8Alpha)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and absence of critical impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.