Description

2,2,2-Trifluoro-N'-Hydroxy-n-Pyrazin-2-Ylethanimidamide is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethyl-substituted pyrazine core. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with enhanced metabolic stability and bioavailability. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule therapeutics, particularly in oncology and antiviral drug discovery.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents, leveraging the trifluoromethyl group to improve pesticidal activity and environmental profile.
• Chemical Biology Probe: Serves as a precursor for labeled compounds or active site inhibitors used in proteomics and target validation studies.
• Material Science Research: Potential building block for specialty polymers or ligands in catalysis due to its electron-deficient heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	2,2,2-Trifluoro-N'-Hydroxy-n-Pyrazin-2-Ylethanimidamide
CAS No.	681249-55-8
Molecular Formula	C7H6F3N5O
Molecular Weight	233.15 g/mol
Synonyms	2,2,2-Trifluoro-N'-hydroxypyrazine-2-carboximidamide; 2-Pyrazinecarboximidamide, N-hydroxy-2,2,2-trifluoro-; 2,2,2-Trifluoroacetimidic acid, N-hydroxy-, 2-pyrazinyl-; Trifluoro-N-hydroxy-n-pyrazin-2-ylethanimidamide; 681249-55-8; N-Hydroxy-2,2,2-trifluoropyrazine-2-carboximidamide
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-N'-Hydroxy-n-Pyrazin-2-Ylethanimidamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.