Description

N1-Di[3,5-Di(trifluoromethyl)phenyl]methyl-3-bromobutanamide is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines a bromoalkylamide core with multiple electron-withdrawing trifluoromethylphenyl groups, making it a valuable precursor for constructing complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting specific receptors or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl groups can improve lipophilicity and biological activity.
• Ligand & Catalyst Development: Acts as a precursor for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the research of advanced polymers and organic electronic materials, where its fluorinated aromatic system can influence electronic properties and stability.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	N1-Di[3,5-Di(trifluoromethyl)phenyl]methyl-3-bromobutanamide
CAS No.	680579-72-0
Molecular Formula	C22H15BrF12N1O1
Molecular Weight	617.25 g/mol
Synonyms	3-Bromo-N-[bis[3,5-bis(trifluoromethyl)phenyl]methyl]butanamide; N-[Bis[3,5-bis(trifluoromethyl)phenyl]methyl]-3-bromobutanamide; 3-Bromo-N-(bis(3,5-di(trifluoromethyl)phenyl)methyl)butyramide; Butanamide, 3-bromo-N-[bis[3,5-bis(trifluoromethyl)phenyl]methyl]-; N-(Bis(3,5-di(trifluoromethyl)phenyl)methyl)-3-bromobutanamide
EINECS	Contact for details

Quality Control

Our N1-Di[3,5-Di(trifluoromethyl)phenyl]methyl-3-bromobutanamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, and our quality system is designed to meet the stringent requirements of global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.