Description

1-Pyrrolidinepropanenitrile,3-Hydroxy-,(3R)-(9Ci) is a chiral, high-purity chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its stereochemically defined pyrrolidine scaffold, which is a privileged structure in medicinal chemistry for constructing bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly those targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drug candidates, especially those containing a 3-hydroxypyrrolidine moiety.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Asymmetric Synthesis: Serves as a chiral ligand precursor or auxiliary in catalytic processes to induce enantioselectivity.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1-Pyrrolidinepropanenitrile,3-Hydroxy-,(3R)-(9Ci)
CAS No.	680223-71-6
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	(3R)-3-Hydroxy-1-pyrrolidinepropanenitrile; (R)-3-Hydroxypyrrolidine-1-propanenitrile; 3-Hydroxy-1-pyrrolidinepropanenitrile, (3R)-; 1-Pyrrolidinepropanenitrile, 3-hydroxy-, (3R)-; (R)-3-(3-Hydroxypyrrolidin-1-yl)propanenitrile; 680223-71-6; (R)-3-Hydroxy-pyrrolidine-1-propionitrile
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinepropanenitrile,3-Hydroxy-,(3R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.