Description

Ethyl 2-(2,6-Difluorophenyl)Acetate is a high-value fluorinated aromatic ester building block, essential for the synthesis of complex organic molecules. Its core value lies in the strategic placement of fluorine atoms on the phenyl ring, which significantly influences the electronic properties, metabolic stability, and lipophilicity of final target compounds. This makes it a critical intermediate for research and development in the pharmaceutical and agrochemical industries, where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of anti-inflammatory, anti-cancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic performance.
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymer backbones, enhancing material properties like chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Catalysis Research: A versatile reagent in cross-coupling reactions, esterifications, and other catalytic processes for constructing complex molecular architectures in R&D laboratories.
• Flavor & Fragrance Industry: Potential use as a precursor for synthesizing novel aromatic esters with unique organoleptic properties.

Basic Information

Item	Details
Product Name	Ethyl 2-(2,6-Difluorophenyl)Acetate
CAS No.	680217-71-4
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	Ethyl (2,6-Difluorophenyl)acetate; 2-(2,6-Difluorophenyl)acetic Acid Ethyl Ester; Ethyl 2,6-Difluorobenzeneacetate; (2,6-Difluorophenyl)acetic Acid Ethyl Ester; Ethyl α-(2,6-Difluorophenyl)acetate; 680217-71-4; Acetic acid, 2-(2,6-difluorophenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2,6-Difluorophenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.