Description

3-Benzyloxy-α-(n-Butyryl)-Aminopropionitrile is a specialized organic nitrile building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the production of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a protected aminopropionitrile moiety.
• Agrochemical Research: Used in the development and scale-up of new herbicides, fungicides, and plant growth regulators.
• Peptidomimetic Synthesis: Serves as a precursor for non-natural amino acid derivatives and peptide analogs in medicinal chemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific nitrile-based architectures.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for method development and exploratory synthesis projects.
• Scale-up & Process Chemistry: Suitable for process optimization and kilogram-scale production under GMP or non-GMP conditions, depending on grade.

Basic Information

Product Name	3-Benzyloxy-α-(n-Butyryl)-Aminopropionitrile
CAS No.	679412-75-0
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	3-(Benzyloxy)-2-[(1-oxobutyl)amino]propanenitrile; 2-[(Butanoyl)amino]-3-(phenylmethoxy)propanenitrile; α-(n-Butyrylamino)-3-benzyloxypropionitrile; N-(1-Cyano-2-benzyloxyethyl)butyramide; 3-Benzyloxy-2-butyrylamino-propionitrile; Butyramide, N-(1-cyano-2-(phenylmethoxy)ethyl)-; (2S)-2-[(Butanoyl)amino]-3-(phenylmethoxy)propanenitrile (for enantiomer)
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-α-(n-Butyryl)-Aminopropionitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our standard grade meets typical research and development specifications, and we can discuss custom synthesis to meet specific pharmaceutical (GMP) or other regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.