Description

Fmoc-3-(3-Thienyl)-Dl-Alanine is a non-natural, protected amino acid derivative designed for solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers incorporating thiophene-based side chains to modulate the physicochemical and biological properties of novel peptides. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic laboratories focused on developing peptide-based therapeutics, diagnostics, and chemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected building block for the automated synthesis of custom peptides.
• Pharmaceutical Research: Incorporation into peptide drug candidates to enhance stability, binding affinity, or membrane permeability via its hydrophobic thienyl moiety.
• Chemical Biology: Synthesis of peptide-based tools and probes for studying protein-protein interactions and enzyme activity.
• Material Science: Potential use in the development of peptide-based biomaterials and supramolecular structures.
• Agrochemical Research: Exploration in the design of novel bioactive peptides for crop protection.
• Academic & Process Development: For method development and scaling up synthetic routes for complex peptide sequences.

Basic Information

Product Name	Fmoc-3-(3-Thienyl)-Dl-Alanine
CAS No.	678991-94-1
Molecular Formula	C22H19NO4S
Molecular Weight	393.45 g/mol
Synonyms	Fmoc-3-(3-thienyl)-DL-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-thienyl)-DL-alanine; Fmoc-DL-3-(3-Thienyl)alanine; Fmoc-β-(3-Thienyl)-DL-alanine; N-Fmoc-3-(3-thienyl)alanine; (RS)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(thiophen-3-yl)propanoic acid; Fmoc-3-Thienyl-DL-Ala-OH; Fmoc-3-(3-Thienyl)Ala
EINECS	Contact for details

Quality Control

Our Fmoc-3-(3-Thienyl)-Dl-Alanine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.