Description

(2,4-Difluoro-Phenyl)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Acetic Acid is a high-purity, protected amino acid derivative designed for advanced organic synthesis. This compound is a critical building block for the development of novel pharmaceuticals and bioactive peptides, offering precise molecular control. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the synthesis of complex peptide-based therapeutics.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid derivative for the controlled assembly of peptide chains.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those targeting specific receptor sites.
• Medicinal Chemistry: Acts as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of compound libraries.
• Bioconjugation: Facilitates the site-specific modification of peptides, proteins, and other biomolecules for diagnostic or therapeutic purposes.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged molecules for studying biological pathways and mechanisms.

Basic Information

Product Name	(2,4-Difluoro-Phenyl)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Acetic Acid
CAS No.	678991-01-0
Molecular Formula	C23H17F2NO4
Molecular Weight	409.38 g/mol
Synonyms	Fmoc-2,4-difluoro-DL-phenylglycine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,4-difluorophenylglycine; Fmoc-(2,4-diF)Phg-OH; N-Fmoc-2,4-difluorophenylglycine; 2,4-Difluoro-DL-phenylglycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; (2,4-Difluorophenyl)((9H-fluoren-9-ylmethoxy)carbonylamino)acetic acid; N-α-Fmoc-2,4-difluorophenylglycine
EINECS	Contact for details

Quality Control

Our (2,4-Difluoro-Phenyl)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.