Description

m-Peg7-4-Nitrophenyl Carbonate is a heterobifunctional polyethylene glycol (PEG) derivative featuring a reactive 4-nitrophenyl carbonate group at one terminus. This compound is a critical reagent for the controlled, amine-selective functionalization of biomolecules and surfaces under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical and bioconjugation sectors for developing advanced drug delivery systems, PEGylated therapeutics, and diagnostic agents.

Application

• Bioconjugation Reagent: For the site-specific PEGylation of peptides, proteins, and antibodies via amine groups.
• Drug Delivery System Development: As a key linker in the synthesis of prodrugs and polymer-drug conjugates to enhance solubility and pharmacokinetics.
• Surface Functionalization: To create hydrophilic, non-fouling coatings on nanoparticles, biosensors, and medical devices.
• Crosslinking Agent: In the preparation of hydrogels and biomaterials for tissue engineering and controlled release applications.
• Diagnostic Reagent Synthesis: For attaching targeting ligands or reporter molecules to carriers in assay development.
• Intermediate in Organic Synthesis: Used in multi-step synthetic routes to create more complex functionalized PEG derivatives.

Basic Information

Product Name	m-Peg7-4-Nitrophenyl Carbonate
CAS No.	678150-56-6
Molecular Formula	C24H39NO13
Molecular Weight	549.57 g/mol
Synonyms	mPEG7-NPC; Methoxy-PEG7-4-nitrophenyl carbonate; α-Methoxy-ω-(4-nitrophenyloxycarbonyl)hepta(ethylene glycol); 4-Nitrophenyl carbonate PEG methyl ether (MW ~550); 1-(4-Nitrophenyl) 1-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl] carbonate; PEG7 methyl ether 4-nitrophenyl carbonate; m-PEG7-NPC; NPC-PEG7-OMe
EINECS	Contact for details

Quality Control

Our m-Peg7-4-Nitrophenyl Carbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and bioconjugation applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and moisture content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Assay	≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.