Description

2-(2,5-Dimethyl-1H-1-pyrrolyl)-3-thiophenecarbohydrazide is a specialized heterocyclic organic compound that serves as a valuable synthetic intermediate and building block in advanced chemical research and development. Its unique molecular architecture, combining pyrrole and thiophene moieties with a carbohydrazide linker, makes it a versatile precursor for the synthesis of complex molecules with potential biological and material science applications. This high-purity chemical is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and academic research institutions focused on developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or ligand in the creation of advanced polymers, coordination complexes, and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme inhibition and protein-ligand interactions.
• Academic & Industrial R&D: Essential reagent for methodological development in organic synthesis and heterocyclic chemistry research programs.
• Coordination Chemistry: Acts as a chelating ligand for transition metals, useful in catalysis and the preparation of metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(2,5-Dimethyl-1H-1-pyrrolyl)-3-thiophenecarbohydrazide
CAS No.	678139-53-2
Molecular Formula	C11H13N3OS
Molecular Weight	235.31 g/mol
Synonyms	3-Thiophenecarbohydrazide, 2-(2,5-dimethyl-1H-pyrrol-1-yl)-; 2-(2,5-Dimethylpyrrol-1-yl)thiophene-3-carbohydrazide; 2-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-thiophenecarbohydrazide; 2,5-Dimethyl-1H-pyrrole-1-carbothiohydrazide (related); Thiophene-3-carbohydrazide, 2-(2,5-dimethyl-1H-pyrrol-1-yl)-; Pyrrolyl-thiophene carbohydrazide; CAS 678139-53-2
EINECS	Contact for details

Quality Control

Our production of 2-(2,5-Dimethyl-1H-1-pyrrolyl)-3-thiophenecarbohydrazide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and handled in a controlled environment suitable for advanced intermediates. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods including HPLC, NMR, and mass spectrometry. We support compliance with global regulatory frameworks such as REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with good laboratory practices for chemical intermediates.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.