Description

Motavizumab is a humanized monoclonal antibody designed for targeted therapeutic intervention. This product is critical for pharmaceutical research and development, offering a high-purity standard essential for preclinical and clinical studies. It is primarily required by biopharmaceutical companies and research institutions focused on developing treatments for respiratory syncytial virus (RSV) infections.

Application

• Pharmaceutical R&D: Primary reagent in the research and development of anti-viral therapeutics targeting RSV.
• Preclinical Studies: Used in animal models to evaluate efficacy, pharmacokinetics, and safety profiles of potential RSV treatments.
• Mechanism of Action Research: Employed in virology and immunology labs to study virus neutralization and host immune response pathways.
• Reference Standard: Serves as a critical reference material for the quality control and validation of biosimilar development processes.
• Diagnostic Development: Potential use in the development of high-sensitivity diagnostic assays for RSV detection and quantification.

Basic Information

Product Name	Motavizumab
CAS No.	677010-34-3
Molecular Formula	Contact for details
Molecular Weight	Approx. 150 kDa (Monoclonal Antibody)
Synonyms	MEDI-524; Numax; Anti-RSV Monoclonal Antibody; Humanized IgG1κ Anti-F Protein Antibody; Recombinant Humanized Anti-RSV Mab; Motavizumab (MEDI-524); Motavizumab-ykro (proposed INN)
EINECS	Contact for details

Quality Control

Our Motavizumab is manufactured under stringent quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, SDS-PAGE and CE-SDS for identity and integrity, and potency assays to ensure biological activity. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. Store in a dedicated freezer with consistent temperature monitoring.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Protein Content (A280)	As per COA
Potency (RSV Neutralization)	≥ 90% relative activity
Endotoxin (LAL)	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.