Description

3-(4-Fluorophenyl)-2,2-Dimethylpropanoic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound is valued for its structural rigidity and the presence of a fluorine atom, which are critical for modulating the physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use as a key intermediate in the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing candidates for central nervous system (CNS) and metabolic disorder therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorophenyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving their chemical resistance and surface properties.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D for constructing complex, fluorinated molecular architectures.
• Peptidomimetics & Bio-conjugates: Used to incorporate non-natural, rigid carboxylic acid components into peptide analogs and bioconjugation linkers.

Basic Information

Product Name	3-(4-Fluorophenyl)-2,2-Dimethylpropanoic Acid
CAS No.	676621-96-8
Molecular Formula	C11H13FO2
Molecular Weight	196.22 g/mol
Synonyms	2,2-Dimethyl-3-(4-fluorophenyl)propanoic Acid; 4-Fluoro-α,α-dimethylbenzenepropanoic Acid; 3-(p-Fluorophenyl)-2,2-dimethylpropionic Acid; p-Fluoro-α,α-dimethylhydrocinnamic Acid; 676621-96-8; Benzenepropanoic acid, 4-fluoro-α,α-dimethyl-; (4-Fluorophenyl)-2,2-dimethylpropanoic Acid
EINECS	Contact for details

Quality Control

Our production of 3-(4-Fluorophenyl)-2,2-Dimethylpropanoic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material for ICH stability studies upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.