Description

Bicyclo[2.2.2]Octane, 2,6-Difluoro-, (2R,6S)-Rel- (9Ci) is a stereochemically defined, fluorinated bicyclic compound of significant interest in advanced organic synthesis. Its rigid, three-dimensional structure and strategically placed fluorine atoms make it a valuable chiral building block for developing novel pharmaceuticals and agrochemicals. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical industry for applications in medicinal chemistry and drug discovery.

Application

• As a chiral synthon and advanced intermediate in the research and development of active pharmaceutical ingredients (APIs).
• Utilized in medicinal chemistry for the synthesis of novel drug candidates, leveraging its fluorinated bicyclic scaffold to modulate biological activity and metabolic stability.
• Potential use in the development of agrochemicals, where the fluorine atoms and rigid structure can enhance product efficacy and environmental profile.
• Application in material science research for creating specialty polymers or liquid crystals with unique properties.
• Serving as a key reference standard or building block in asymmetric synthesis and methodology development within academic and industrial laboratories.

Basic Information

Product Name	Bicyclo[2.2.2]Octane, 2,6-Difluoro-, (2R,6S)-Rel- (9Ci)
CAS No.	676565-44-9
Molecular Formula	C8H12F2
Molecular Weight	146.18 g/mol
Synonyms	rel-(2R,6S)-2,6-Difluorobicyclo[2.2.2]octane; (2R,6S)-2,6-Difluorobicyclo[2.2.2]octane; 2,6-Difluorobicyclo[2.2.2]octane, (2R,6S)-rel-; Bicyclo[2.2.2]octane, 2,6-difluoro-, (2R,6S)-rel-; 676565-44-9; (rel-2R,6S)-2,6-Difluorobicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane, 2,6-Difluoro-, (2R,6S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical identity verification, to ensure it meets the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.