Description

Phenylalanine, n-[(1,1-Dimethylethoxy)Carbonyl]-N,β,β-Trimethyl- is a protected amino acid derivative, specifically a tert-butoxycarbonyl (Boc)-protected trimethylphenylalanine analog. This compound is a critical building block in advanced organic synthesis, particularly for the production of peptides and peptidomimetics where precise stereochemistry and side-chain protection are required. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Biochemical Research: Used in academic and industrial R&D for studying protein-protein interactions, enzyme mechanisms, and structure-activity relationships (SAR).
• Proteomics & Diagnostics: Employed in the development of labeled peptides, affinity tags, and molecular probes for diagnostic assays.
• Agrochemical Development: Potential intermediate in the synthesis of specialized bioactive compounds for crop protection.

Basic Information

Product Name	Phenylalanine, n-[(1,1-Dimethylethoxy)Carbonyl]-N,β,β-Trimethyl-
CAS No.	676487-35-7
Molecular Formula	C17H25NO4
Molecular Weight	307.39 g/mol
Synonyms	Boc-N-Me-β,β-Me2-Phe-OH; N-(tert-Butoxycarbonyl)-N-methyl-3,3-dimethylphenylalanine; Boc-3,3-dimethyl-N-methyl-L-phenylalanine; (2S)-3-[3,3-Dimethylphenyl]-2-[(2-methylpropan-2-yl)oxycarbonyl(methyl)amino]propanoic acid; N-Boc-N-methyl-3,3-dimethyl-L-phenylalanine; N-[(1,1-Dimethylethoxy)carbonyl]-N-methyl-3,3-dimethyl-L-phenylalanine; Boc-N-Me-Dmp-OH
EINECS	Contact for details

Quality Control

Our Phenylalanine, n-[(1,1-Dimethylethoxy)Carbonyl]-N,β,β-Trimethyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and specific rotation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions (e.g., nitrogen or argon atmosphere) to prevent degradation upon repeated opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.