Description

Fmoc-Glycyl-D-Mannosamine CAS NO 676248-84-3 is a high-purity, protected amino sugar derivative designed for advanced chemical synthesis. This compound is a critical building block for the solid-phase and solution-phase synthesis of complex glycopeptides and glycoconjugates, enabling precise control over carbohydrate-protein linkages. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutics, vaccines, and diagnostic tools that target glycosylation pathways.

Application

• Glycopeptide Synthesis: A key intermediate for the controlled incorporation of D-mannosamine into peptide backbones.
• Glycoconjugate Vaccine Development: Used in the research and production of carbohydrate-based antigens.
• Chemical Biology Probes: Enables the creation of labeled or modified sugars for studying glycosylation and carbohydrate-protein interactions.
• Pharmaceutical Intermediate: Serves as a precursor in the synthesis of potential drug candidates targeting infectious diseases, cancer, and metabolic disorders.
• Oligosaccharide Assembly: Facilitates the stepwise construction of complex oligosaccharide structures in automated synthesizers.
• Bioconjugation: Used for site-specific attachment of carbohydrate motifs to proteins, antibodies, or other biomolecules.

Basic Information

Product Name	Fmoc-Glycyl-D-Mannosamine
CAS No.	676248-84-3
Molecular Formula	C23H26N2O8
Molecular Weight	458.46 g/mol
Synonyms	Fmoc-Gly-D-ManN; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycyl-D-mannosamine; Fmoc-Gly-D-Mannosamine; (2R,3S,4R,5R)-2-[[(2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]acetyl]amino]-3,4,5-trihydroxyhexanal; Fmoc-Gly-D-ManNH2; Fmoc-Gly-β-D-ManN; Glycyl-D-mannosamine N-Fmoc derivative
EINECS	Contact for details

Quality Control

Our Fmoc-Glycyl-D-Mannosamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and optical rotation for stereochemical integrity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.