Description

7.8-Difluoro-2-Naphthol is a high-purity fluorinated naphthol derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic placement of fluorine atoms on the naphthalene ring, which significantly alters electronic properties and enhances metabolic stability in final compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries, where it is used to construct complex molecules for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing fluorinated drug candidates with improved bioavailability and target selectivity.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to enhanced efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic display materials, contributing to improved charge transport and thermal stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique chemical resistance, lower dielectric constants, or specific optical properties.
• Dye & Pigment Intermediate: Utilized in the production of high-performance, light-fast fluorinated dyes and organic pigments.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and structure-activity relationships.

Basic Information

Product Name	7.8-Difluoro-2-Naphthol
CAS No.	675132-42-0
Molecular Formula	C₁₀H₆F₂O
Molecular Weight	180.15 g/mol
Synonyms	2-Naphthol, 7,8-difluoro-; 7,8-Difluoronaphthalen-2-ol; 7,8-Difluoro-2-hydroxynaphthalene; 7,8-Difluoro-β-naphthol; 2-Hydroxy-7,8-difluoronaphthalene; 7,8-Difluoro-2-naphthalenol
EINECS	Contact for details

Quality Control

Our 7.8-Difluoro-2-Naphthol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your process development and scale-up needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.