Description

7,8-Difluoro-3,4-Dihydronaphthalen-2(1H)-One is a high-purity fluorinated organic building block, a key intermediate in advanced chemical synthesis. Its value lies in its unique difluorinated tetralone structure, which is crucial for introducing fluorine atoms into complex molecules to modulate their biological activity and physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research where fluorination is a common strategy.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging fluorine's ability to enhance compound stability and membrane permeability.
• Material Science Research: Serves as a precursor for fluorinated organic electronic materials, liquid crystals, and advanced polymers requiring specific electronic properties.
• Chemical Biology Probes: Employed in the creation of fluorinated probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	7,8-Difluoro-3,4-Dihydronaphthalen-2(1H)-One
CAS No.	675132-40-8
Molecular Formula	C₁₀H₈F₂O
Molecular Weight	182.17 g/mol
Synonyms	7,8-Difluoro-1,2,3,4-tetrahydronaphthalen-2-one; 7,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone; 7,8-Difluoro-2-tetralone; 2-Tetralone, 7,8-difluoro-; 7,8-Difluoro-3,4-dihydronaphthalen-2(1H)-one; 7,8-Difluoro-α-tetralone
EINECS	Contact for details

Quality Control

Our 7,8-Difluoro-3,4-Dihydronaphthalen-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.