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1-(2-Methoxyphenyl)-2-(Dicyclohexylphosphino)Pyrrole CAS NO 672937-63-2


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CAS No.:672937-63-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(2-Methoxyphenyl)-2-(Dicyclohexylphosphino)Pyrrole is a specialized organophosphorus ligand with a unique steric and electronic profile. This compound matters for its critical role in facilitating challenging cross-coupling and hydrogenation reactions in pharmaceutical and fine chemical synthesis. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials industries seeking to optimize catalytic processes.

Application

  • As a ligand in transition metal catalysis, particularly for palladium- and nickel-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination).
  • For the development of novel catalytic systems in academic and industrial research laboratories.
  • In the synthesis of active pharmaceutical ingredients (APIs) and complex organic intermediates requiring selective transformations.
  • As a key component in asymmetric catalysis for the production of enantiomerically pure compounds.
  • For hydrogenation and hydrofunctionalization reactions in fine chemical manufacturing.
  • In material science research, particularly in the development of novel organometallic complexes and polymers.

Basic Information

Product Name 1-(2-Methoxyphenyl)-2-(Dicyclohexylphosphino)Pyrrole
CAS No. 672937-63-2
Molecular Formula C23H32NOP
Molecular Weight 369.48 g/mol
Synonyms 2-(Dicyclohexylphosphino)-1-(2-methoxyphenyl)-1H-pyrrole; (2-Methoxyphenyl)[2-(dicyclohexylphosphino)pyrrol-1-yl]methane; Dcypp; JohnPhos-type Pyrrole Ligand; 1-(2-Methoxyphenyl)-2-(dicyclohexylphosphanyl)-1H-pyrrole
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Quality Control

Our 1-(2-Methoxyphenyl)-2-(Dicyclohexylphosphino)Pyrrole is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by NMR (1H, 13C, 31P) and HPLC analysis. Certificates of Analysis (COA) detailing purity, identity, and relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. The material is easily oxidized and light-sensitive; prolonged exposure to air or ambient light should be avoided. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item Specification
Appearance White to off-white solid
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
31P NMR Purity Conforms
Solubility Soluble in common organic solvents (THF, Toluene, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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