Description

(1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-Bis(3,5-Di-T-Butylsalicylidene)Cobalt(Iii) p-Toluenesulfonate Monohydrate is a high-purity, chiral salen-type cobalt(III) complex salt, widely recognized for its role as a versatile and efficient catalyst. Its primary commercial value lies in enabling highly enantioselective transformations, which are critical for producing optically active intermediates in pharmaceutical and fine chemical synthesis. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts for asymmetric synthesis.

Application

• Asymmetric Catalysis: A key catalyst for enantioselective epoxidation, cyclopropanation, and other C-H functionalization reactions.
• Pharmaceutical Intermediate Synthesis: Used in the production of chiral active pharmaceutical ingredients (APIs) and key synthons.
• Agrochemical Research: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Facilitates the synthesis of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic & Industrial R&D: A valuable reference standard and catalyst for method development in organic and organometallic chemistry.
• Polymer Science: Investigated for use in the synthesis of chiral polymers and materials with specific optical properties.

Basic Information

Product Name	(1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-Bis(3,5-Di-T-Butylsalicylidene)Cobalt(III) p-Toluenesulfonate Monohydrate
CAS No.	672306-06-8
Molecular Formula	C48H68CoN2O7S
Molecular Weight	876.06 g/mol
Synonyms	(1S,2S)-(+)-1,2-Diaminocyclohexane-N,N'-bis(3,5-di-tert-butylsalicylidene)cobalt(III) p-toluenesulfonate monohydrate; (S,S)-(+)-Jacobsen's Catalyst p-Toluenesulfonate Salt Monohydrate; Cobalt(III)-salen complex p-tosylate; (S,S)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(III) p-toluenesulfonate hydrate; (S,S)-Co(salen)OTs·H2O; Chiral Cobalt Salen Catalyst; [N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(III) 4-methylbenzenesulfonate monohydrate
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-Bis(3,5-Di-T-Butylsalicylidene)Cobalt(III) p-Toluenesulfonate Monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for catalytic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific rotation is provided with every shipment to guarantee traceability and performance consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	Dark brown to black crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (ee)	≥ 99.0%
Specific Rotation [α]D20	+400° to +440° (c = 0.1 in CHCl3)
Water Content (KF)	2.0 - 4.0% (Theoretical for monohydrate: ~2.06%)
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.