Description

Acetamide, n-[3-Oxo-1-(Trifluoromethyl)Propyl]- is a specialized fluorinated acetamide derivative, identified by CAS NO 669692-57-3. This compound is valued for its unique trifluoromethyl ketone moiety, which imparts distinct reactivity and physicochemical properties critical for advanced chemical synthesis. It serves as a key building block or intermediate for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a strategic design element to enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Advanced Material Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and coatings with tailored surface properties.
• Chemical Biology & Proteomics: Employed as a reactive handle or probe in the study of enzyme mechanisms and protein labeling due to its ketone functionality.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes for constructing complex molecules, including natural product analogs and diagnostic agents.

Basic Information

Product Name	Acetamide, n-[3-Oxo-1-(Trifluoromethyl)Propyl]-
CAS No.	669692-57-3
Molecular Formula	C7H8F3NO2
Molecular Weight	195.14 g/mol
Synonyms	4,4,4-Trifluoro-3-oxobutanamide; 4,4,4-Trifluoroacetoacetamide; 3-Oxo-4,4,4-trifluorobutanamide; N-(3-Oxo-1-(trifluoromethyl)propyl)acetamide; 4,4,4-Trifluoro-3-oxo-N-(prop-2-en-1-yl)butanamide (related); TFAA derivative; Trifluoromethyl ketone acetamide; 1,1,1-Trifluoro-2,4-dioxopentane amide
EINECS	Contact for details

Quality Control

Our production of Acetamide, n-[3-Oxo-1-(Trifluoromethyl)Propyl]- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets precise customer specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and commercial projects requiring compliance with ISO, GMP, and REACH standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.