Description

2-[Bis(3,5-Dimethylphenyl)Phosphino]Benzaldehyde is a specialized organophosphorus ligand featuring a formyl group, making it a versatile building block in advanced chemical synthesis. Its primary value lies in its ability to coordinate with transition metals, forming highly active and selective catalysts for critical cross-coupling and hydrogenation reactions. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise control over stereochemistry and reaction pathways to develop novel active ingredients and complex molecules.

Application

• As a key ligand in the development of palladium and rhodium-based catalysts for Suzuki-Miyaura, Heck, and other cross-coupling reactions.
• Utilized in asymmetric hydrogenation processes to produce chiral intermediates for active pharmaceutical ingredients (APIs).
• Employed in academic and industrial research for exploring new catalytic systems and reaction methodologies.
• Serves as a precursor for the synthesis of more complex, bidentate phosphine ligands via reactions at the aldehyde functional group.
• Applied in the manufacture of fine chemicals and specialty materials where high selectivity and yield are paramount.
• Potential use in material science for creating metal-organic frameworks (MOFs) or functional surfaces.

Basic Information

Product Name	2-[Bis(3,5-Dimethylphenyl)Phosphino]Benzaldehyde
CAS No.	669091-00-3
Molecular Formula	C23H23OP
Molecular Weight	346.40 g/mol
Synonyms	2-(Bis(3,5-dimethylphenyl)phosphanyl)benzaldehyde; (2-Formylphenyl)bis(3,5-dimethylphenyl)phosphine; Benzaldehyde, 2-[bis(3,5-dimethylphenyl)phosphino]-; 2-(Di(3,5-xylyl)phosphino)benzaldehyde
EINECS	Contact for details

Quality Control

Our production of 2-[Bis(3,5-Dimethylphenyl)Phosphino]Benzaldehyde adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity, critical for catalytic performance. Each lot is analyzed using advanced techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.