Description

n-(Fmoc-5-Amino-3-Oxa-Pentyl)-Succinamic Acid is a specialized, high-purity building block designed for advanced peptide synthesis and bioconjugation. This compound is critical for researchers and manufacturers requiring precise, reliable, and scalable Fmoc-protected intermediates to construct complex molecular architectures. It is primarily utilized in pharmaceutical R&D, proteomics, and the development of novel therapeutic peptides and antibody-drug conjugates (ADCs).

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid derivative for the controlled assembly of peptide chains.
• Linker Chemistry for ADCs: Serves as a functionalized spacer or linker component in the design of antibody-drug conjugates, enabling stable payload attachment.
• Proteomics Research: Used in the synthesis of activity-based probes, affinity tags, and other tools for studying protein function and interactions.
• Combinatorial Library Synthesis: A valuable building block for generating diverse libraries of peptide-like compounds for drug discovery screening.
• Bioconjugation and Labeling: Facilitates the site-specific modification of proteins, antibodies, and other biomolecules with labels, drugs, or polymers.
• Custom Peptide Service: An essential raw material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke peptide production.

Basic Information

Product Name	n-(Fmoc-5-Amino-3-Oxa-Pentyl)-Succinamic Acid
CAS No.	669073-62-5
Molecular Formula	C24H26N2O7
Molecular Weight	454.47 g/mol
Synonyms	Fmoc-8-amino-3,6-dioxaoctanoic acid; Fmoc-Adoo-OH; 5-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino-3-oxapentyl]succinamic acid; Nα-Fmoc-8-amino-3,6-dioxaoctanoic acid; Fmoc-N-amido-PEG2-acid; Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid (related PEG linker); Fmoc-PEG2-CH2CH2COOH; N-(2-{2-[2-(Fmoc-amino)ethoxy]ethoxy}ethyl)succinamic acid
EINECS	Contact for details

Quality Control

Our n-(Fmoc-5-Amino-3-Oxa-Pentyl)-Succinamic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and cGMP manufacturing. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); desiccate upon opening and handle under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.