Description

Bis[2-(Di-I-Propylphosphino)-4-Methylphenyl]Amine is a specialized, high-purity organophosphorus ligand with the CAS number 666856-94-6. This compound matters for its critical role as a sophisticated catalyst component in advanced chemical synthesis, enabling highly selective and efficient reactions. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel synthetic routes and optimizing production processes.

Application

• As a key ligand in homogeneous catalysis, particularly for cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig).
• In the synthesis of active pharmaceutical ingredients (APIs) and complex organic intermediates requiring high stereoselectivity.
• For catalyst development and optimization in academic and industrial research laboratories.
• In the manufacture of advanced materials and specialty polymers where precise molecular control is required.
• As a precursor for other functionalized phosphine ligands used in organometallic chemistry.
• For asymmetric hydrogenation and other chiral transformations in fine chemical production.

Basic Information

Product Name	Bis[2-(Di-I-Propylphosphino)-4-Methylphenyl]Amine
CAS No.	666856-94-6
Molecular Formula	C29H47NP2
Molecular Weight	471.62 g/mol
Synonyms	Bis[2-(Diisopropylphosphino)-4-methylphenyl]amine; DavePhos; Di(1-adamantyl)-n-butylphosphine (common ligand class name); 2-(Diisopropylphosphino)-N-[2-(diisopropylphosphino)-4-methylphenyl]-4-methylaniline; N,N-Bis[2-(diisopropylphosphino)-4-methylphenyl]amine; Phosphine ligand 666856-94-6; Buchwald-type ligand; Arylphosphine ligand.
EINECS	Contact for details

Quality Control

Our Bis[2-(Di-I-Propylphosphino)-4-Methylphenyl]Amine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, essential for catalytic performance. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP and ISO 9001 standards where applicable, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.