Description

L-Valine, 3-Methyl-n-(Trifluoroacetyl)- (9Ci) is a specialized, high-purity chemical intermediate featuring a trifluoroacetyl protecting group on a modified valine backbone. This compound is critical for advanced organic synthesis, particularly in the development of novel pharmaceuticals and bioactive peptides where precise stereochemistry and functional group manipulation are required. It serves as a key building block for researchers and manufacturers in pharmaceutical R&D, agrochemical synthesis, and advanced material science who demand reliable, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex active pharmaceutical ingredients (APIs), especially for peptide-based drugs and protease inhibitors.
• Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid derivative, enabling the controlled elongation of peptide chains.
• Agrochemical Development: Serves as a precursor in creating novel herbicides, fungicides, or plant growth regulators with enhanced activity and selectivity.
• Bioconjugation & Probe Synthesis: Utilized for labeling biomolecules or creating molecular probes for diagnostic and biochemical research due to its reactive trifluoroacetyl group.
• Material Science: Acts as a monomer or modifier in the synthesis of specialized polymers and advanced materials with tailored properties.
• Chemical Biology Studies: Employed to investigate enzyme mechanisms or protein-protein interactions by incorporating this modified amino acid into substrate analogs.

Basic Information

Item	Detail
Product Name	L-Valine, 3-Methyl-n-(Trifluoroacetyl)- (9Ci)
CAS No.	666832-71-9
Molecular Formula	C8H12F3NO3
Molecular Weight	227.18 g/mol
Synonyms	N-(Trifluoroacetyl)-3-methyl-L-valine; (2S)-2-[(Trifluoroacetyl)amino]-3-methylbutanoic acid; 3-Methyl-N-(trifluoroacetyl)-L-valine; L-Valine, N-trifluoroacetyl-3-methyl-; N-Trifluoroacetyl-3-methyl-L-valine; TFA-3-methyl-L-valine; (S)-2-(Trifluoroacetamido)-3-methylbutanoic acid
EINECS	Contact for details

Quality Control

Our L-Valine, 3-Methyl-n-(Trifluoroacetyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.