Description

tert-Butyl 4-Iodo-2-Methylphenylcarbamate is a specialized aromatic carbamate derivative, serving as a high-value chemical intermediate in advanced organic synthesis. Its core value lies in the strategic placement of iodine and the tert-butoxycarbonyl (Boc) protecting group, making it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry for creating libraries of novel bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a versatile intermediate in cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive aryl iodide moiety.
• Protecting Group Chemistry: The Boc group is utilized for the temporary protection of amine functionalities during multi-step synthetic sequences.
• Material Science Research: Potential precursor for the development of organic electronic materials and liquid crystals.
• Chemical Biology Probes: Can be used to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	tert-Butyl 4-Iodo-2-Methylphenylcarbamate
CAS No.	666746-27-6
Molecular Formula	C12H16INO2
Molecular Weight	333.17 g/mol
Synonyms	Boc-4-Iodo-2-methylaniline; 4-Iodo-2-methylphenylcarbamic Acid tert-Butyl Ester; tert-Butyl N-(4-Iodo-2-methylphenyl)carbamate; 2-Methyl-4-iodophenylcarbamic Acid tert-Butyl Ester; N-Boc-4-Iodo-2-methylaniline; N-(tert-Butoxycarbonyl)-4-iodo-2-methylaniline; 1-(tert-Butoxycarbonylamino)-4-iodo-2-methylbenzene
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Iodo-2-Methylphenylcarbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.