Description

Acetamide, n-(Cyclopentylmethyl)-2,2,2-Trifluoro- (9Ci) is a specialized trifluoroacetamide derivative, a high-value intermediate in advanced organic synthesis. Its molecular structure, featuring a cyclopentylmethyl group and a trifluoroacetyl moiety, makes it a critical building block for creating complex molecules with targeted properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to introduce fluorinated motifs that can dramatically alter a compound's metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring fluorinated amide or peptide backbones to enhance potency and pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to improved lipophilicity and environmental stability.
• Material Science Research: Acts as a monomer or modifying agent in the development of specialty polymers and advanced materials, where fluorine incorporation can impart unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry and catalysis research to construct sophisticated ligands that modulate metal center reactivity for more efficient synthetic transformations.
• Fluorine Chemistry Building Block: A versatile reagent for introducing the -COCF3 group into complex molecular architectures, a common strategy in medicinal and process chemistry.

Basic Information

Product Name	Acetamide, n-(Cyclopentylmethyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	666262-49-3
Molecular Formula	C9H14F3NO
Molecular Weight	209.21 g/mol
Synonyms	N-(Cyclopentylmethyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(cyclopentylmethyl)acetamide; N-Cyclopentylmethyltrifluoroacetamide; Trifluoroacetic acid cyclopentylmethylamide; (Cyclopentylmethyl)carbamoyl fluoride; Acetamide, N-(cyclopentylmethyl)-2,2,2-trifluoro-; TFA-Cyp-Methyl-amide
EINECS	Contact for details

Quality Control

Every batch of Acetamide, n-(Cyclopentylmethyl)-2,2,2-Trifluoro- (9Ci) is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.