Description

Carbamic Acid, [(3S,5S)-5-(Hydroxymethyl)-3-Pyrrolidinyl]-, 1,1-Dimethylethyl Ester is a high-purity, stereochemically defined chiral intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key building block for the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of a protected pyrrolidine derivative to advance their synthetic routes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Protease Inhibitor Synthesis: Serves as a key precursor in the development of protease inhibitors, a major class of antiviral and anticancer agents.
• Agrochemical Research: Used in the discovery and development of novel, stereoselective pesticides and herbicides.
• Asymmetric Catalysis Ligand Precursor: Provides a chiral scaffold for the development of novel ligands used in asymmetric synthesis.
• Peptidomimetics & Bioactive Molecule Construction: Integral for building peptidomimetic structures and other complex molecules that mimic natural peptides.
• Academic & Process R&D: A valuable reagent for research institutions and process development teams exploring new synthetic methodologies.

Basic Information

Product Name	Carbamic Acid, [(3S,5S)-5-(Hydroxymethyl)-3-Pyrrolidinyl]-, 1,1-Dimethylethyl Ester
CAS No.	663948-85-4
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	(3S,5S)-5-(Hydroxymethyl)-3-pyrrolidinol, 1,1-dimethylethyl carbamate; tert-Butyl (3S,5S)-5-(hydroxymethyl)-3-pyrrolidinylcarbamate; (3S,5S)-5-(Hydroxymethyl)-3-pyrrolidinylcarbamic Acid tert-Butyl Ester; (3S,5S)-N-Boc-5-(hydroxymethyl)-3-pyrrolidinol; (3S,5S)-N-Boc-5-(hydroxymethyl)-3-aminopyrrolidine; (3S,5S)-5-(Hydroxymethyl)-3-pyrrolidinamine, N-Boc-; (3S,5S)-N-Boc-3-amino-5-(hydroxymethyl)pyrrolidine; BOC-(3S,5S)-3-Amino-5-hydroxymethyl-pyrrolidine
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(3S,5S)-5-(Hydroxymethyl)-3-Pyrrolidinyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.