Description

Ethyl(2,5-Difluorophenyl)Acetate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate, enabling the efficient introduction of a difluorophenyl moiety into complex molecular architectures. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Advanced Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering their surface properties, chemical resistance, and thermal stability.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CROs/CMOs serving the life sciences sector.
• Academic & Industrial Research: Utilized in methodological chemistry research and for creating specialized chemical libraries for high-throughput screening.

Basic Information

Product Name	Ethyl(2,5-Difluorophenyl)Acetate
CAS No.	662138-60-5
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	Ethyl 2-(2,5-Difluorophenyl)acetate; 2-(2,5-Difluorophenyl)acetic Acid Ethyl Ester; Acetic Acid, 2-(2,5-Difluorophenyl)-, Ethyl Ester; Ethyl (2,5-Difluorobenzene)acetate; Ethyl 2,5-Difluorophenylacetate; 662138-60-5; Ethyl α-(2,5-Difluorophenyl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl(2,5-Difluorophenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining under an inert atmosphere to preserve optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.