Description

3-Amino-3-(Trifluoromethyl)Piperidin-2-One is a high-value, fluorinated piperidinone derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a trifluoromethyl group on the same carbon, makes it indispensable for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe: Employed in medicinal chemistry to introduce fluorine atoms into bioactive molecules, studying structure-activity relationships (SAR).
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers with unique surface properties.

Basic Information

Product Name	3-Amino-3-(Trifluoromethyl)Piperidin-2-One
CAS No.	662108-92-1
Molecular Formula	C6H9F3N2O
Molecular Weight	182.15 g/mol
Synonyms	3-Amino-3-(trifluoromethyl)piperidin-2-one; 3-Amino-3-(trifluoromethyl)-2-piperidinone; 2-Piperidinone, 3-amino-3-(trifluoromethyl)-; 3-Amino-3-trifluoromethylpiperidin-2-one; 3-(Trifluoromethyl)-3-aminopiperidin-2-one; 3-Amino-3-(trifluoromethyl)-2-piperidone; (Rac)-3-Amino-3-(trifluoromethyl)piperidin-2-one
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(Trifluoromethyl)Piperidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.