Description

2,4-Difluoro-2'-cyanobiphenyl-5-boronic acid is a high-value, multi-functional boronic acid derivative used as a key synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing biphenyl scaffolds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific fluorinated and cyanated biphenyl structures.
• Material Science: Serves as a precursor in the development of organic electronic materials, including OLEDs and semiconductors, where its molecular structure contributes to desired electronic properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new carbon-carbon bond formation methodologies and creating compound libraries.
• Ligand Synthesis: Can be utilized to synthesize novel ligands for catalysis, leveraging the boronic acid group for further functionalization.

Basic Information

Product Name	2,4-Difluoro-2'-cyanobiphenyl-5-boronic Acid
CAS No.	660425-28-5
Molecular Formula	C13H8BF2NO2
Molecular Weight	259.02 g/mol
Synonyms	5-Borono-2,4-difluoro-2'-cyanobiphenyl; (5-(2-Cyano-2,4-difluorobiphenyl))boronic Acid; 2,4-Difluoro-2'-cyano-[1,1'-biphenyl]-5-boronic Acid; 2'-Cyano-2,4-difluorobiphenyl-5-boronic Acid; B-[5-(2-Cyano-2,4-difluorobiphenyl)]boronic Acid; 660425-28-5; 2,4-Difluoro-2-Cyanobibenzen-5-Boronic Acid
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-2'-cyanobiphenyl-5-boronic acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.