Description

1-Boc-4-(Cyanoacetyl)Piperidine is a high-purity, protected piperidine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in the dual functionality of the cyanoacetyl and Boc-protected amine groups, enabling precise and efficient construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those containing piperidine scaffolds.
• API Development: Used in research and development for constructing novel Active Pharmaceutical Ingredients (APIs) with targeted therapeutic effects.
• Agrochemical Synthesis: Serves as a building block for creating advanced crop protection agents and pesticides.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biological studies.
• Peptidomimetics: Facilitates the creation of peptide-like compounds with enhanced stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	1-Boc-4-(Cyanoacetyl)Piperidine
CAS No.	660406-84-8
Molecular Formula	C13H20N2O3
Molecular Weight	252.31 g/mol
Synonyms	1-Boc-4-(2-cyanoacetyl)piperidine; tert-Butyl 4-(2-cyanoacetyl)piperidine-1-carboxylate; 4-(Cyanoacetyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(cyanoacetyl)piperidine; Piperidine, 4-(2-cyanoacetyl)-, 1-(1,1-dimethylethyl) ester; BOC-4-(Cyanoacetyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(Cyanoacetyl)Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects with material suitable for research use and can supply grades aligned with current Good Manufacturing Practice (cGMP) principles for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.