Description

Benzamide, 4-Fluoro-n-[(1R,2S)-2-Phenylcyclopropyl]-, Rel-(-)- (9Ci) CAS NO 658684-16-3 is a high-purity, chiral organic compound featuring a fluorinated benzamide structure fused with a phenylcyclopropyl moiety. This specific stereochemistry makes it a valuable advanced pharmaceutical intermediate for the research and development of novel active ingredients. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical synthesis facilities focused on creating targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors due to its benzamide scaffold and specific stereochemistry.
• Chemical Biology Probes: Serves as a precursor for labeled compounds used in target identification and validation studies.
• Asymmetric Synthesis: Employed as a chiral auxiliary or reagent in stereoselective chemical transformations.
• Agrochemical Research: Investigated as an intermediate for novel crop protection agents with specific biological activity.
• Academic & Industrial R&D: Utilized in research institutions and corporate R&D centers for exploratory synthesis and method development.

Basic Information

Item	Detail
Product Name	Benzamide, 4-Fluoro-n-[(1R,2S)-2-Phenylcyclopropyl]-, Rel-(-)- (9Ci)
CAS No.	658684-16-3
Molecular Formula	C16H14FNO
Molecular Weight	255.29 g/mol
Synonyms	rel-(-)-4-Fluoro-N-[(1R,2S)-2-Phenylcyclopropyl]benzamide; (1R,2S)-N-(4-Fluorobenzoyl)-2-phenylcyclopropanamine; 4-Fluoro-N-[(1R,2S)-2-phenylcyclopropyl]benzamide; Benzamide, 4-fluoro-N-[(1R,2S)-2-phenylcyclopropyl]-, rel-(-)-; (-)-4-Fluoro-N-[(1R,2S)-2-phenylcyclopropyl]benzamide; rel-(1R,2S)-N-(4-Fluorobenzoyl)-2-phenylcyclopropanamine
EINECS	Contact for details

Quality Control

Our production of Benzamide, 4-Fluoro-n-[(1R,2S)-2-Phenylcyclopropyl]-, Rel-(-)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including HPLC, chiral chromatography, NMR, and mass spectrometry. Comprehensive Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.