Description

Benzamide, 4-Fluoro-n-[(1R,2S)-2-Phenylcyclopropyl]-, Rel-(+)- (9Ci) is a high-purity, chiral organic compound featuring a fluorinated benzamide scaffold attached to a phenylcyclopropyl moiety. This specific stereochemistry makes it a valuable chiral building block and intermediate in advanced pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its defined stereochemistry and fluorinated aromatic ring.
• Agrochemical Synthesis: Acts as a precursor in the development of novel pesticides and herbicides, leveraging the biological activity of the benzamide core.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Asymmetric Catalysis Ligand Precursor: Potential use in the synthesis of chiral ligands for asymmetric synthesis applications.
• Reference Standard: Used as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Benzamide, 4-Fluoro-n-[(1R,2S)-2-Phenylcyclopropyl]-, Rel-(+)- (9Ci)
CAS No.	658684-14-1
Molecular Formula	C16H14FNO
Molecular Weight	255.29 g/mol
Synonyms	(1R,2S)-N-(4-Fluorobenzoyl)-2-phenylcyclopropanamine; rel-(+)-4-Fluoro-N-[(1R,2S)-2-phenylcyclopropyl]benzamide; 4-Fluoro-N-[(1R,2S)-2-phenylcyclopropyl]benzamide; Benzamide, 4-fluoro-N-[(1R,2S)-2-phenylcyclopropyl]-, rel-(+)-; (1R,2S)-2-Phenylcyclopropyl 4-fluorobenzamide; 658684-14-1; 4-Fluoro-N-((1R,2S)-2-phenylcyclopropyl)benzamide
EINECS	Contact for details

Quality Control

Our production of Benzamide, 4-Fluoro-n-[(1R,2S)-2-Phenylcyclopropyl]-, Rel-(+)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.