Description

3-Oxatricyclo[4.2.1.02,5]Non-7-Ene,4,4-Difluoro-(9Ci) is a specialized fluorinated bicyclic ether building block of significant interest in advanced organic synthesis. Its unique strained-ring structure, incorporating both an oxa-bridge and geminal difluoro groups, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those requiring fluorinated, conformationally constrained scaffolds to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and resins with tailored thermal or chemical resistance properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chelating ligands or catalyst frameworks that leverage its unique steric and electronic profile.
• Fluorine Chemistry Research: A valuable substrate for studying ring-opening reactions, fluorination mechanisms, and the behavior of strained heterocyclic systems under various conditions.

Basic Information

Item	Details
Product Name	3-Oxatricyclo[4.2.1.02,5]Non-7-Ene,4,4-Difluoro-(9Ci)
CAS No.	658074-45-4
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	4,4-Difluoro-3-oxatricyclo[4.2.1.02,5]non-7-ene; 4,4-Difluoro-3-oxatricyclo[4.2.1.0²,⁵]non-7-ene; 3-Oxa-4,4-difluorotricyclo[4.2.1.02,5]non-7-ene; Difluorinated oxatricyclononene; Fluorinated bicyclic ether; 658074-45-4; 9CI numbered derivative of oxatricyclononene.
EINECS	Contact for details

Quality Control

Every batch of 3-Oxatricyclo[4.2.1.02,5]Non-7-Ene,4,4-Difluoro-(9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by GC/HPLC), identity confirmation, and impurity profiles. Our commitment to reliable supply and transparent documentation supports critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.