Description

tert-Butyl 3-Amino-4-Fluorobenzylcarbamate is a high-purity, fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: The carbamate-protected amine functionality makes it valuable for constructing peptide analogs and protease inhibitors.
• Material Science Precursor: Employed in the synthesis of monomers for specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes.

Basic Information

Product Name	tert-Butyl 3-Amino-4-Fluorobenzylcarbamate
CAS No.	657409-24-0
Molecular Formula	C12H17FN2O2
Molecular Weight	240.28 g/mol
Synonyms	1. tert-Butyl N-[(3-Amino-4-fluorophenyl)methyl]carbamate 2. 3-Amino-4-fluorobenzylcarbamic acid tert-butyl ester 3. Boc-3-Amino-4-fluorobenzylamine 4. N-Boc-3-Amino-4-fluorobenzylamine 5. 1-[(tert-Butoxycarbonyl)amino]methyl-2-fluoro-5-aminobenzene 6. (3-Amino-4-fluorobenzyl)carbamic acid 1,1-dimethylethyl ester 7. tert-Butyl (3-amino-4-fluorobenzyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Amino-4-Fluorobenzylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.