Description

Boronic Acid, (2-Cyano-6-Fluorophenyl)- (9Ci) is a high-purity, functionalized boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its unique bifunctional structure, featuring both a boronic acid group for Suzuki-Miyaura cross-coupling and a cyano substituent for further derivatization, enabling the synthesis of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in novel drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides requiring specific fluorinated and nitrile-containing structures.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and organoboron chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where its functional groups allow for precise tuning of electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors that leverage boronic acid-diol interactions for detection applications.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences industry with tailored, complex organic molecules.

Basic Information

Product Name	Boronic Acid, (2-Cyano-6-Fluorophenyl)- (9Ci)
CAS No.	656235-44-8
Molecular Formula	C7H5BFNO2
Molecular Weight	164.93 g/mol
Synonyms	(2-Cyano-6-fluorophenyl)boronic acid; 2-Cyano-6-fluorobenzeneboronic acid; 6-Fluoro-2-cyanophenylboronic acid; (6-Fluoro-2-cyanophenyl)boronic acid; Boronic acid, B-(2-cyano-6-fluorophenyl)-; 2-Fluoro-6-cyanophenylboronic acid; B-(2-Cyano-6-fluorophenyl)boronic acid; 656235-44-8
EINECS	Contact for details

Quality Control

Every batch of Boronic Acid, (2-Cyano-6-Fluorophenyl)- (9Ci) is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.