Description

(11Ar)-10,11,12,13-Tetrahydro-N,n-Bis[(1S)-1-Phenylethyl]-Diindeno[7,1-De:1',7'-Fg][1,3,2]Dioxaphosphocin-5-Amine is a sophisticated chiral phosphine-amine ligand with a complex, rigid diindeno-dioxaphosphocin backbone. This compound matters for its exceptional ability to induce stereoselectivity in transition metal-catalyzed reactions, a critical factor in the synthesis of high-value, single-enantiomer products. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for applications such as asymmetric hydrogenation and cross-coupling.

Application

• Asymmetric Catalysis: As a privileged chiral ligand for rhodium, iridium, and palladium complexes in enantioselective hydrogenation and other C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and infectious diseases.
• Agrochemical Research: Development of novel, stereochemically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential use in the synthesis of chiral polymers or as a component in advanced catalytic systems for specialty chemicals.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	(11Ar)-10,11,12,13-Tetrahydro-N,n-Bis[(1S)-1-Phenylethyl]-Diindeno[7,1-De:1',7'-Fg][1,3,2]Dioxaphosphocin-5-Amine
CAS No.	656233-47-5
Molecular Formula	C41H36NOP
Molecular Weight	589.71 g/mol
Synonyms	(11aR)-N,N-Bis[(1S)-1-Phenylethyl]-10,11,12,13-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-amine; (R)-DTBM-SEGPHOS Amine Derivative; Chiral Diindeno-Dioxaphosphocin Ligand; (11aR)-DTBM-SEGPHOS-based Amine; (S,S)-Phenylethyl-Diindenophosphine Amine; CAS 656233-47-5; DTBM-SEGPHOS Amine Analog
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral ligand adheres to stringent quality protocols. Every batch undergoes comprehensive analysis, including Chiral HPLC to confirm enantiomeric excess (typically >99%) and ¹H/³¹P NMR for structural verification and purity assessment. Certificates of Analysis (COA) with full analytical data are provided to ensure traceability and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Under these conditions, the product is stable for extended periods. For long-term storage beyond two years, consideration should be given to storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.