Description

1H-Pyrazole-1-Carboxamide,n-(1R,3R,5R)-1-Azabicyclo[3.2.1]Oct-3-Yl-4- is a specialized organic compound with a complex bicyclic structure, serving as a critical intermediate in advanced pharmaceutical synthesis. Its precise stereochemistry and functional groups make it a valuable building block for medicinal chemistry research and development. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly those targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological targets.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalytic systems or receptor-binding studies.
• Chemical Biology Probes: Acts as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Process Chemistry Development: Serves as a critical intermediate during the scale-up and route scouting for potential drug candidates.

Basic Information

Product Name	1H-Pyrazole-1-Carboxamide,n-(1R,3R,5R)-1-Azabicyclo[3.2.1]Oct-3-Yl-4-
CAS No.	655786-23-5
Molecular Formula	C11H16N4O
Molecular Weight	220.27 g/mol
Synonyms	(1R,3R,5R)-3-[(1H-Pyrazol-1-yl)carboxamido]-1-azabicyclo[3.2.1]octane; (1R,3R,5R)-N-(1-Azabicyclo[3.2.1]oct-3-yl)-1H-pyrazole-1-carboxamide; Troparil Intermediate; Bicyclic Pyrazole Carboxamide; Tropane-based Pyrazole Derivative; 1-Azabicyclo[3.2.1]oct-3-amine, N-(1H-pyrazol-1-ylcarbonyl)-, (1R,3R,5R)-
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-1-Carboxamide,n-(1R,3R,5R)-1-Azabicyclo[3.2.1]Oct-3-Yl-4- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be aligned with client requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.